Propofol Infusion Syndrome：Rare, but Lethal. Do Not Overlook It

Abstract

Propofol is a remarkable anesthetic agent which is widely used in general anesthesia and intensive care. However, while propofol infusion syndrome（PRIS）is a rare complication related to high-dose propofol infusion, it is potentially fatal. Further, the mechanism of PRIS remains unclear, and there is no effective treatment. Although PRIS usually occurs with large doses of propofol administered for an extended period, a recent case report described its occurrence with low-dose propofol infusion. Hence, we need to increase our knowledge of PRIS.