Effects of Sugammadex on the Need for Postoperative Mechanical Ventilation in Patients with Myasthenia Gravis

Abstract

Previous studies have demonstrated that sugammadex can provide a reliable neuromuscular recovery from rocuronium-induced neuromuscular blockade（NMB）in patients with myasthenia gravis（MG）. We divided MG patients undergoing extended thymectomy into two groups based on reversal of NMB with sugammadex（S group, n=31）or no reversal of NMB（C group, n=15）and retrospectively compared their need for postoperative mechanical ventilation in the intensive care unit. More patients in the S group received rocuronium than patients in the C group（p=0.011）. The number of patients requiring postoperative mechanical ventilation in the intensive care unit was not significantly different between the two groups（6 cases in the S group vs. 4 cases in the C group）.