Evaluation of Epidural Buprenorphine for Postoperative Pain Relief

A Controlled Comparison with Epidural Morphine

Abstract

In a controled trial, epidural buprenorhine was compared with epidural morphine for the pain relief after the simple hysterectomy. Buprenorphine 0.1mg or morphine 2mg dissolved in 10ml of physiological saline or 1% mepivacaine were given into epidural space on demand for the first 12 hours after the operation. Buprenorphine, as judged by an assessment of pain score, produced prolonged analgesia as long as morphine, and more rapid analgesia than morphine.