Abstract
Conditions of 54 neonates born from mothers given premedication of 10mg of Deazepam and 240mg of Lidocain for local anesthesia during Cesarean section under epidural lumbar anesthesia were assessed during the early neonatal period. Transmission of Diazepam from mother to child and its concentration in the blood plasma of neonate and mother were also studied.
In the 30 minutes from administration of 10mg of Diazepam to delivery, the C/M ratio was 0.47 in the case of intramuscular injection, 0.85 for intravenous injection and 0.21 for oral administration.
In 16 cases of selective cesareansection, Diazepam could hardly be detected in the neonates'plasma after 24hrs.
General assessment of 40 neonates born under selective cesarean section revealed normal spontanous motor activity and symmetrical posture and no hypotonia.
Hematoaerometer reading's indicated normal levels while no hyperventilation nor anomalous respiration patterns were observed.
