Abstract
Endometrium could show variable histological and cytological changes in the carcinogenesis step and in response to various stimuli, e. g., endometrial polyp, endometritis, leiomyoma, and climacterium. It is often difficult to discern neoplastic changes from physiological changes in biopsy and cytology because these morphologic changes may occur together with neoplasm but also occur independently. We must there-fore observe endometrial histology and cytology from structural and cytological viewpoints to avoid misdiagnosis.
Histological glandular crowding in endometrium corresponds to cytological glandular variability in structure. We present structural variation seen under variable benign conditions. Cytological atypia are frequently confusing because cellular changes seen in ischemic endometrium could show atypia that hampers correct diagnosis. We present a case of anovulatory endometrial cytology. We should avoid considering this type of cellular atypia as neoplastic, but this type of atypia may be seen in endometrial proliferative diseases and adenocarcinoma. If we see this degenerative atypia, we must pay attention to background cells to search for more definite atypia.
