2008 Volume 47 Issue 5 Pages 367-371
Background : We report a case of oncocytic myoepithelioma of the parotid gland, and discuss its cytology and diagnosis differentiating it from other salivary tumors with oncocytic or eosinophilic cells.
Case : A 60-year-old woman seen for a mass in the left neck was found in computed tomography (CT) and magnetic resonance imaging (MRI) to have a 2.5×2.0 cm tumor of the left parotid gland. Aspiration cytology showed a large number of clustered and isolated cells with voluminous eosinophilic cytoplasm and round nuclei. Smaller cells forming tightly cohesive clusters were also seen, as was the transition between eosinophilic and smaller cells. Based on histological and immunohistochemical findings, the tumor was definitively diagnosed as oncocytic myoepithelioma.
Conclusions : Oncocytic myoepithelioma is a rare neoplasm of the salivary gland that should be included in the differential diagnosis of salivary gland aspiration when smears contain oncocytic or eosinophilic cells.