Abstract
Objective : We analyzed uterine-body endometrioid adenocarcinoma (EMA) cells appearing in the peritoneal cavity.
Study Design : Cases were 33 EMA specimens surgically resected from 2000 to 2006 and consisting of 17 G1 (51.5%), 13 G2 (39.4%), and 3 G3 (9.1%). Focusing on squamous metaplastic-like cells (SMC) using immunohisto/cytochemical tests, we analyzed cytohistological findings and their association with pathological conditions such as histological grade, depth, tumor size, and location.
Results : Peritoneal cytological findings were as follows : large to small papillary G1 or G2 clusters and scattered G3 patterns. SMC appeared in clumps and scattered : 1+at 33.3%, 2+at 55.6%, 3+at 11.1%, and 61.1% for G1, 33.4% for G2, and 5.5% for G3. These features were found to be related to diffuse tumor location but not to invasion depth or tumor size.
Conclusions : SMC appears to be a hallmark in peritoneal uterine-body EMA cytology, especially in G1 or G2 diagnosis.