Abstract
Objective : We reviewed the meaning of koilocytosis in cytology and histology in diagnosing HPV-related squamous uterine cervix lesions.
Study Design : We analyzed the frequency and differential diagnosis of koilocytosis by reexamining cytological specimens with low grade squamous intraepithelial lesions (LSIL) and histological specimens of mild dysplasia (CIN 1).
Results : Of 55 cytological LSIL cases, 23 (42%) had koilocytosis. Of the 29 CIN 1 biopsy specimen, 19 (65.5%) had koilocytosis.
Conclusions : Koilocytosis is thus useful in evaluating the effects of HPV infection and diagnosing cervical intraepithelial neoplasia. Koilocytosis is, in cytology, the most important finding for differentiating LSIL from other nonneoplastic cytological changes and HSIL.
