The Journal of the Japanese Society of Clinical Cytology
Online ISSN : 1882-7233
Print ISSN : 0387-1193
ISSN-L : 0387-1193
Clinical Articles
Adenoid cystic carcinoma of the uterine cervix with atypical squamous cells
Sayaka INOUEHiroaki KASEToshihiko IKARASHI
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JOURNAL FREE ACCESS

2013 Volume 52 Issue 4 Pages 350-353

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Abstract
Background : Adenoid cystic carcinoma affects mainly the salivary glands. It is a extremely rare tumor accounting for<1% of adenocarcinoma of the uterine cervix. We report herein on a case of primary adenoid cystic carcinoma stageIb2 with atypical squamous cells.
Case : An 80-year-old woman with massive genital bleeding was brought to the emergency room. The swelling of the uterine cervix and a scraping smear and biopsy specimens suggested adenoid cystic carcinoma.
Cytologically, the tumor cells were dispersed as single cells, and demonstrated a high N/C ratio. There were many dense aggregates of cells and cysts of a cribriform appearance. In part, the mass contained mucinous materials.
The histological analysis of the tumor cells demonstrated a mixed solid and cribriform pattern. This is recognized as a feature of adenoid cystic carcinoma.
Conclusion : Adenoid cystic carcinomas have aggregates of tumor cells contained in cysts with pale mucinous materials, and may have atypical squamous cells. Adenoid cystic carcinoma is a extremely rare tumor and the optimal definitive treatment has not yet been established. The prognosis is not good, therefore, the diagnosis should be performed carefully.
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© 2013 The Japanese Society of Clinical Cytology
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