Abstract
A 61-year-old man underwent distal gastrectomy for gastric cancer. Two years after the surgery, chest CT revealed a nodular lesion in the lung. Lobectomy was performed because primary lung cancer was suspected by the preoperative cytology. Finally, histopathologial examination of the resected specimen revealed the nodule as a metastasis from gastric cancer. The tumor stump cytology showed a necrotic background and cell clusters with three-dimensional tubular structures. The nuclei showed a coarsely granular chromatin pattern with prominent nucleoli. Moreover, the nuclei also showed focal TTF-1 immunoexpression.
Diagnostic approaches combining cytology and clinical information are advisable to improve the yield for accurate diagnosis of pulmonary malignancies.
