Abstract
We report the case of a female patient in her 70’s with poorly differentiated carcinoma of the thyroid gland. Fine needle aspiration cytology showed epithelial clusters with irregular nuclear margins and nuclear grooves, as well as intracytoplasmic lumina formation. Whole-body imaging revealed no tumorous lesions in any anatomic site other than the thyroid gland. Cytologists should recognize that intracytoplasmic lumina may be observed in neoplastic lesions of thyroid gland.