2019 Volume 58 Issue 4 Pages 162-166
Objective : This study was performed to investigate the clinical management of women with cytological findings of atypical squamous cells, cannot exclude high-grade squamous intraepithelial lesions (ASC-H).
Study Design : In this retrospective study, 80 women underwent colposcopic biopsies after cytological classification of ASC-H. We examined the histologic diagnosis at the initial biopsy. Clinical outcomes were also assessed for the follow-up cases.
Results : The initial biopsy revealed cervical intraepithelial neoplasia grade 3 (CIN 3) in 37.5% of patients, CIN2 in 11.3%, CIN1 in 12.5%, micro-invasive cancer in 5.0%, and carcinosarcoma of the uterine corpus in 1.2%. Forty-four women (55.0%) were diagnosed as having CIN ≥2. Among 22 follow-up cases, 6 were diagnosed as having CIN2 or CIN3 (median, 16 months ; range, 10-32 months).
Conclusion : A prompt cervical colposcopic biopsy is essential for women with cytological findings of ASC-H. For women with a benign lesion at the initial cervical biopsy, repeating the cytological examination can aid in the selection of high-risk cases.
