The Journal of the Japanese Society of Clinical Cytology
Online ISSN : 1882-7233
Print ISSN : 0387-1193
ISSN-L : 0387-1193
Clinical Articles
Two cases of ovarian cancer detected by endometrial cytology
Tomoka MAEHANAYuki YAMADASumire SUGIMOTOTomoko UCHIYAMARyuji KAWAGUCHIChiho OHBAYASHIHiroshi KOBAYASHI
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2020 Volume 59 Issue 6 Pages 299-304

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Abstract

Background : Endometrial smear cytology is currently one of the most common methods used to detect endometrial cancer. While no conclusive method has been established yet to detect ovarian cancer, ovarian cancer can sometimes be incidentally detected through endometrial cancer screening.

Cases : Case 1 : A 58-year-old female presented with cytologic abnormalities detected during endometrial cancer screening. The endometrial biopsy results were negative, and computerized tomography (CT) and magnetic resonance imaging (MRI) findings were unremarkable. An exploratory laparoscopic surgery was performed owing to inconsistencies between the cytology and imaging findings. The final diagnosis was serous borderline tumor of the left ovary. Case 2 : A 51-year-old woman consulted her doctor with a 1-year history of persistent cough and palpitations. She was diagnosed as having pleural mesothelioma from the imaging findings and tumor biopsy. After completion of chemotherapy, gynecological cancer was suspected. An exploratory laparotomy was performed, and she was diagnosed as having high grade serous carcinoma of the left ovary.

Conclusion : We diagnosed two cases of ovarian cancer by endometrial cytology, despite the lack of remarkable CT or MRI findings. Extrauterine tumors should be suspected if aggregates of tumor cells are found to coexist with normal atrophic endometrial cells on endometrial cytology.

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© 2020 The Japanese Society of Clinical Cytology
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