2024 Volume 63 Issue 1 Pages 25-27
In this article, we present a case of a parotid gland nodule, in which the aspiration cytology specimen showed amylase crystalloids. The patient, a woman in her 70 s, diagnosed as having a nodule in the left parotid region, was referred to our otolaryngology department. Imaging revealed a well-demarcated nodule measuring approximately 20 mm in diameter. Aspiration cytology showed a large number of crystalloids with inflammatory cells. Immunocytochemically, these crystalloids were positive for α-amylase. It is important to consider the possibility of amylase crystalloids in cases where the aspiration cytology specimens show crystalloids of various shapes.