Behavior of Biopolymers, Cytoskeleton, DNA, and Phospholipids, that Exert Self-organization, Shown in the Liquid-Liquid Phase Separation

Abstract

Reproducing the dynamics of proteins and/or nucleic acids in a solution in which microdroplets of the similar size as cells or organelles are emerged by liquid-liquid phase separation, is an excellent model system. This is a powerful and rewarding strategy for understanding the properties of living cells. The targets of that research also include the formation of membraneless organelles, which has been gaining more attention in recent years. Here, the current results of our research using representative biopolymers, actin cytoskeleton and DNA, and phospholipids that are important components of biological membranes, would be introduced.