Gastric Biopsy and Brushing Cytology under Direct Vision by Gastrofiberscope

Abstract

Gastric brushing cytology and biopsy under direct visionby gastrofiberscope were performed to about 2500 casesduring the periods from 1972 to 1977. We compared theresults of gastric cytology with the results of gastric biopsy, and studied the problems of gastric cytodiagnosis.
1) By biopsy, positive results were obtained in 93.1% ofcarcinomas and by cytology in 88.3%.
When gastricbiopsy and cytology were combined, positive results wereraised to 96.6%.
2) There were two false positive cases (0.08%) bycytodiagnosis.These clinical final diagnoses were allbenign gastric ulcers.
In these cases, we overdiagnosedhigh grade atypical hyperplasti ccells into carcinoma cells.
3) In benign lesions, there were eighteen cases of suspicious for malignancy. By retrospective studies, weconsidered that these cells were atypical regenerative cells, atypical hyperplastic cells, atypical intestinal metaplasticcells and benign signet ring cells.
In cases that the lesion has not been brought into thecenter of the visual field because of stenosis or location, gastric brushing cytology should be done.