Abstract
For earlier and more accurate cytological diagnosis of non-neoplastic endometrium, endometrial hyperplasia, and endometrial cancer in patients with metrorrhagia, we attempted a screening using a scoring system for endometrial cytology.
1) From the mean score calculated retrospectively in 122 patients aged 30 years or above (97 with normal endometrium, 8 with endometrial hyperplasia, 5 atypical endometrial hyperplasia, 12 with endometrial cancer), scores of 0-6 were regarded as indicating normal endometrium, 7-12 as hyperplasia, and 13-18 as endometrial cancer.
2) The accuracy by prospective scoring in 3 patients with cystic glandular hyperplasia, 9 with adenomatous hyperplasia, 11 with adenocarcinoma endometrial type G 1, and 3 with adenocarcinoma endometrial type G 3 was 73.3%, 80.0%, 88.6%, 100% and 100%, respectively.
3) The frequency of false nagative findings in hyperplasia or more serious conditions was 6.2% and was 0% in cancer alone. False positive findings were obtained in 7.5% of subjects with normal endometrium, and in only 1.2% of subjects with normal endometrium had scores of 13 or above.
These results suggest the applicability of screening for endometrial neoplasia using this scoring method.
