Abstract
Cytologic studies of cerebrospinal fluid (CSF) in infiltrating lobular carcinoma of both breasts with carcinomatous meningitis is reported. The patient, a 32-year-old woman, complained of mass lesions in both breasts and abdominal fullness. CT scanning revealed swelling of both ovaries, ascites and pleural effusion. The patient underwent ovariectomy and biopsy of both breasts. These lesions were diagnosed histo pathologically as invasive lobular carcinoma. Seven months later, she had headache, nausea an vomiting, and was readmitted. Meningeal carcinomatosis was diagnosed by cytological examination of the CSF. The examination revealed the following cytological characteristics. Cancer cells were scattered, solitary or arranged in sheets. There were also some paired cells. Autopsy revealed carcinoma cells around small vessels in the subarachnoid space.
