A study on cytodiagnoses by PTCD (Percutaneous Transhepatic Cholargiography and Drainage) in 89 cases
1993 Volume 32 Issue 4 Pages 502-506
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1993 Volume 32 Issue 4 Pages 502-506
We analyzed cytodiagnoses based on 125 samples of PTCD (percutaneous transhepatic cholangiography and drainage) fluid from 89 patients at Tottori Prefectural Central Hospital during the five years from 1986 to 1991. Diagnoses were comfirmed by histological examination and/or by the patients' course.
1. The results of PTCD-cytodiagnosis were excellent. The validity rate was 74.4% as a whole and rose to 85.9% when cases in which there was failure to obtain evaluable cells were excluded.
2. The important findings in PTCD-cytodiagnosis were loose cellular connections, variable internuclear distance, thickening of the nuclear rim, necrotic background and an increase in nuclear chromatin. When average nuclear size, the most objective finding in cytology, exceeded a diameter of 9μm the probability of malignancy was extremely high.
3. Twenty-four false-negative tests were demonstrated, 4 cases of under evaluation of the cellular picture and 20 cases of unsuccessful collection of evaluable cells.
4. There were 8 false-positive tests. In spite of the review, 4 yielded cytologically malignant findings.
5. In 40 tests (32%) there was failure to obtain proper cells. It is important to improve the method of collecting PTCD fluid, which would rise the accuracy of PTCDcytodiagnosis.
