1993 Volume 32 Issue 4 Pages 543-546
Two cases of secretory carcinoma of the breast, in a 55-and 53-year-old woman, are reported. Aspiration biopsy cytology revealed some characteristic features. Many malignant cells were scattered in Papanicolaou smears from case 1, with mild atypia. A few clusters of more atypical cells were observed in smears from case 2. So-called “mucous globular str uctures (MGS) ”, “clusters like bunches of grapes” and “punched out lesions” were observed in the smears from both cases.
Histologically, a typical pattern of secretory caricnoma was seen in the histologic mastectomy specimens from both cases and partial atypical features of a signet-ring cell carcinoma-like pattern were found in case 2.
In cytologic diagnosis, it is important to find “MGS” and “bunches of grapes” in as piration smears of secretory carcinoma of the breast.
