Expression of tumor markers in uterine sarcoma: Immunocytochemical study

Abstract

Expression of the tumor markers in uterine sarcomas was investigated using immunocytochemistry. We found that several tumor markers were expressed heterogeneously in uterine sarcomas as well as in the epithelial tumors. Carcinoembryonic antigen, a-fetoprotein, NCCCO 450, epithelial membrane antigen and sialyl Tn were expressedin uterine sarcomas significantly higher than controls.
Understanding of the tumor markers in uterine sarcoma may contribute to the detection of the disease at early stage. Immunocytochemistry of tumor markersas functional molecules may be very useful to understand biological behavior of uterine sarcoma.