Can Cell-Sweep predict the margin of endocervical extension of CIN before conization in order to decrease surgical margin positive conization?

Abstract

At present, conization, LEEP and Laser evaporation are frequently carried out to treat CIN. Although we can detect the ectocervical margin of CIN by colposcopy before surgical treatment, we can not detect the endocervical margin of CIN before surgical excision. Therefore, we attempted to ascertain the endocervical margin of CIN before surgical excision by employing a Cell-Sweep.
Results: The Cell-Sweep method can detect the endocervical margin of CIN within a 7 mm margin of error by measuring the abnormal cell distribution on a glass slide. Therefore, this method is predicted to be useful for performing more accurate conization.