A case of meningioma with marked infiltration into diploic spaces

Abstract

Background: We report a case of meningioma, in which intraoperative histologic and cytologic consultation was useful in the diagnosis.
Case: A patient had a tumor within the left margo supraorbitalis and temporal bone. A crush preparation and a biopsy specimen from the tumor revealed spindle or polyhedral atypical cells with whorl formation. Intranuclear cytoplasmic inclusions and proteinous hyaline materials were also observed. Histologic examination revealed transitional cell type meningioma with marked infiltration into the diploic space. The MIB-1 positive rate was 2.5% of the tumor cells.
Conclusion: The high index of MIB-1 positivity of the present case may be related to the marked infiltration into the diploic space.