1999 Volume 38 Issue 6 Pages 578-582
Background: Primary serous adenocarcinoma of the uterine cervix is very rare. We report a case of primary serous adenocarcinoma of the uterine cervix that was very sensitive to chemotherapy.
Case: The presenting manifestation of this case, a 58-year-old woman, was abnormal cells on a routine cervical Papanicolaou smear with metastasis to the left scalenlymphnode tumor. On cytological examination, there was a ten dency for malignant cells to from clusters with stratification. Their nuclei showed anisonucleosis with remarkable nucleoli. Microscopic examination revealed serous adenocarcinoma indistinguishable from typical endocervical adenocarcinoma. She was treated by radical hysterectomy after neoadjuvant chemotherapy (cisplatin+5-fluorouracil) and postoperative chemotherapy.
Conclusion: This case suggests that serous adenocarcinoma of the uterine cervix is very sensitive to cisplatin+5-fluorouracil, like serous ovarian cancer.
