1999 Volume 38 Issue 6 Pages 591-596
Background: Carcinosarcoma arising from the uterine body, which often appears in the menopausal women, is an uncommon tumor compared to other malignancies of the uterine body. Usually it has a poor prognosis, so early diagnosis is important, but it is very difficult to diagnose correctly before surgery. We report a case of heterologous carcinosarcoma which appeared on the uterine body, which was characterized by squamous differentiation.
Case: An 88-year-old woman complaining of genital bleeding was examined at a private clinic. The cytological diagnosis of uterine cervix proved to be Class III b, with cartilaginous components found in the necrotic tissue. It was originally suspected to be carcinosaecoma with cartilagious tissue. By re-examination, both endometrioid adenocarcinoma and squamous metaplasia with nuclear atypia was found in the endometrium, so surgical operation was performed under suspicion of endometrial carcinoma.
Conclusion: Based on histological examination before the surgical operation and histopathological findings and results of immunohistochemistry, this case was diagnosed as heterologous carcinosarcoma with squamous differentiation arising from the endometrium.
