1999 Volume 38 Issue 6 Pages 597-601
Background: Endometrial stromal sarcoma is a rare malignant tumor, most of which are diagnosed by histopathology. We describe a case of endometrial stromal sarcoma diagnosed by endometrial scraping cytology before the operation.
Case: The patient was a 50-year-old woman. Preoperative endometrial scraping cytology revealed many atypical round or spindle-shaped cells. The cytoplasm of these cells were scanty and light-greenish, and the nuclei were round with evenly distributed granular nucleolar chromatin. Pleomorphic tumor cells with large nuclei were also recognized. The tumor was diagnosed as endometrial stromal sarcoma because of the cytologic features. Histologically, the tumor was composed of round or spindle-shaped cells, and they were positively immunostained with antibodies for vimentin, αl-antitrypsin and αl-antichymotrypsin.
Conclusion: We report the cytological findings of endometrial stromal sarcoma, a rare malignant tumor, with new immunohistochemical features.