Abstract
Objective: When endometrial cytology suggests endometrioid adenocarcinoma, glandular cell clumps are analyzed.
Study Design: In 40 patients with endometrioid adenocarcinoma G 1, we studied the incidence of highly dense glandular and dendritic clumps and the number of glandular lumens in highly dense glandular clumps, and compared them with atypical endometrial and complex endometrial hyperplasia.
Results: 1) The incidence of highly dense glandular clumps was high compared to that of dendritic clumps.
2) The mean number of glandular lumens in highly dense glandular clumps was 16.9 in endometrioid adenocarcinoma, 11.7 in atypical endometrial hyperplasia, and 6.5 in complex endometrial hyperplasia, all statistically significant (p<0.01)
15glandular lumens may be associated with lesions other than atypical endometrial hyperplasia and more than 21 with endometrioid adenocarcinoma.
Conclusion: Observation of the glandular lumen number in highly dense glandular clumps is important in cytodiagnosis and is useful in general judgment taken together with other items of diagnostic factors.
