The Journal of the Japanese Society of Clinical Cytology
Online ISSN : 1882-7233
Print ISSN : 0387-1193
ISSN-L : 0387-1193
A case of localized epithelial mesothelioma with extramural growth of jejunum
Nozomu KUROSEEriko KINOSHITAMichiho TAKENAKAToshie TERAUCHIManabu YAMASHITAYoshifumi ASAKURAMariko NAKANOTakayuki NOJIMA
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2005 Volume 44 Issue 4 Pages 230-234

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Abstract

Background: We report a case of histological, imprint-cytologicy and electron microscopicy findings on localized epithelial mesothelioma with extramural growth of the jejunum.
Case: A 32-year-old woman admitted to give birth to her second child 1 year ago was laboratory examination after a normal delivery to have progressive anemia and elevated CRP. Computed tomography showed a solid intrapelvic mass with a 5.5 cm cystic lesion in the jejunum, necessitating partial jejunal resection. The jejunal tumor showed extramural growth. Histologically, the tumor was epithelial mesothelioma with cystic formation and severe inflammatory cell infiltration. Electron microscopy examination showed long microvilli. No recurrence or metastasis has been seen in the 1.5 years since surgery.
Conclusion: Cytologically, it is difficult to differentiate between reactive mesothelial cells and tumor cells, although a tumor and malignant mesothelioma an be differentiated. In tumor etiology, we concluded that no relation ship eristed between asbestos and chronic peritoneal irritation because no mesothelial hyperplasia or inflammatory reaction in the peritoneum was seen. Stromal inflammatory cells infiltration suggests a tumor associated immunological tissue reaction. Compared to diffuse mesothelioma, prognosis in this case may be extremely good, but that careful follow-up is needed.

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