2006 Volume 45 Issue 2 Pages 141-146
Objective: We reviewed problems with the diagnosis and theclinical management of adenoma malignum of the uterine cervix.
Study Design: Using the criteria proposed by Tsuda et al., we clinicopathologically reexamined all cases previously diagnosed as adenoma malignum at the Kanagawa cancer center.
Results: When 6 previously diagnosed cases of adenoma malignum were reexamined, only one of the cases met the new criteria. Consequently, adenoma malignum accounted for only 0.1% of all cancers of the uterine cervix in a similar age group. Conization was sometimes difficult to evaluate in cases of suspected adenoma malignum. In addition, characteristic cytological findings were not always recognized.
Conclusion: The recognition of conization is desirable for the diagnosis of adenoma malignum. Adenoma malignum is very rare. A multi-institutional study is needed to determine the optimal management of this disease.
