Xeroderma pigmentosum(XP)is an autosomal recessive genetic disease of DNA repair, which may cause severe sun sensitivity and early development of skin cancers such as squamous cell carcinoma, basal cell carcinoma, and malignant melanoma. The incidence of malignant tumors is particularly high in XP Group A patients, who may require repeated surgical treatment. In addition, XP Group A patients often have delayed mental development, which may make postoperative wound management difficult; thus, it is necessary to take these factors into account when deciding on a reconstruction method. In this study, we experienced a case of basal cell carcinoma in the left lower eyelid of a 10-year-old male patient with XP-Group A. Considering the patient’s age and the fact that he was an XP patient, we performed reconstruction using the periosteal anchoring technique and reported an excellent postoperative course.