Journal of the Japanese Society of Computational Statistics
Online ISSN : 1881-1337
Print ISSN : 0915-2350
ISSN-L : 0915-2350
SAMPLE SIZE DETERMINATION BASED ON MID-P VALUE FOR USE WITH THE TESTING IN 2×2 COMPARATIVE TRIALS
Manabu IwasakiTakuo Tanida
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1994 年 7 巻 1 号 p. 57-64

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In testing two binomial probabilities Fisher's exact test is known to be too conservative. As a consequence, it requires a larger sample size than expected to detect statistical significance. The use of mid-P value instead of the ordinary P-value in the testing would be one possibility to resolve such conservatism. This article investigates how much sample size can be reduced by adopting the mid-P value. It is shown that the sample sizes are almost comparable to those of unconditional tests. A table of sample sizes is given for the reasonable range of parameters to achieve the power of 0.8 or more when the significance level is 0.05.
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© The Japanese Society of Computational Statistics
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