2012 Volume 22 Issue 3 Pages 317-321
We retrospectively analyzed 27 patients with T3 laryngeal carcinoma treated at our department from 2004 to 2008. The patients ranged from 38 to 73 years of age (median: 62) and consisted of 24 men and 3 women. Cases included 21 supraglottic and 6 glottic. Of the 27 patients, 7 were treated by total laryngectomy, 14 by chemoradiotherapy and 6 by radiation alone. The 3-year disease-specific survival rate was 85.7% for operative cases, 77.9% for chemoradiotherapy cases, and 66.7% for radiotherapy cases. In the sixth edition of the UICC staging system, paraglottic space invasion was added as a factor in T3-stage carcinoma. The 3-year disease-specific survival rate was 100% for the cases of paraglottic space invasion, 70.0% for the cases of vocal cord fixation, and 53.6% for the cases of preepiglottic space invasion. These results suggest that the cases of paraglottic space invasion showed a good prognosis, and that laryngeal preservation is indicated.
