Abstract
A retrospective study was conducted to evaluate the clinical outcomes of 32 patients with advanced squamous cell carcinoma of the tongue in our hospital between January 2010 and December 2013. All patients underwent surgical resection. Patients who had microscopically involved resection margins, extranodal extension-positive,pT4,or pN2-3 underwent postoperative chemoradiation therapy. The 3- and 5-year overall survival rates were both 100% in stage Ⅲ, and 74% and 64% in stage Ⅳ. The overall survival rates in patients with microscopically involved resection margins and/or extranodal extension-positive were significantly lower than in the others (p=0.04).