While leukemia occasionally occurs during the course of severe infection, it can be difficult to differentiate whether leukocytosis is caused by infection or leukemia. We herein present a patient who was brought to our hospital for the first time with disseminated intravascular coagulation (DIC) caused by deep cervical cellulitis. Subsequently, the patient was strongly suspected to have acute leukemia, and was thus transferred to the hematology department.