口腔扁平苔癬の治療方法とその臨床評価に関する文献レビューとタスクフォースコンセンサス

川又 均; 伊東 大典; 津島 文彦; 中村 誠司; 河野 憲司; 菅原 由美子; 森山 雅文; 岩渕 博史; 安彦 善裕; 前田 初彦; 杉田 好彦; 長谷川 博雅; 小宮山 雄介; 白石 怜; 和久井 崇大

doi:10.6014/jjsom.29.21

Review

Narrative Review and Task Force Consensus of Current Treatment Methods and Clinical Evaluation of the Outcome for Oral Lichen Planus

Hitoshi KAWAMATA, Daisuke ITO, Fumihiko TSUSHIMA, Seiji NAKAMURA, Kenji KAWANO, Yumiko SUGAWARA, Masafumi MORIYAMA, Hiroshi IWABUCHI, Yoshihiro ABIKO, Hatsuhiko MAEDA, Yoshihiko SUGITA, Hiromasa HASEGAWA, Yuske KOMIYAMA, Ryo SHIRAISHI, Takahiro WAKUI

Author information

Hitoshi KAWAMATA
Chairman of 2^nd OLP Working Group （OLP Committee）, Japanese Association of Oral Medicine
Department of Oral and Maxillofacial Surgery, Dokkyo Medical University School of Medicine
Daisuke ITO
Vice chairman of 2^nd OLP Working Group （OLP Committee）, Japanese Association of Oral Medicine
Fumihiko TSUSHIMA
Committee member of 2^nd OLP Working Group （OLP Committee）, Japanese Association of Oral Medicine
Seiji NAKAMURA
Committee member of 2^nd OLP Working Group （OLP Committee）, Japanese Association of Oral Medicine
Kenji KAWANO
Committee member of 2^nd OLP Working Group （OLP Committee）, Japanese Association of Oral Medicine
Yumiko SUGAWARA
Committee member of 2^nd OLP Working Group （OLP Committee）, Japanese Association of Oral Medicine
Masafumi MORIYAMA
Committee member of 2^nd OLP Working Group （OLP Committee）, Japanese Association of Oral Medicine
Hiroshi IWABUCHI
Committee member of 2^nd OLP Working Group （OLP Committee）, Japanese Association of Oral Medicine
Yoshihiro ABIKO
Committee member of 2^nd OLP Working Group （OLP Committee）, Japanese Association of Oral Medicine
Member of The Japanese Society of Oral Pathology
Hatsuhiko MAEDA
Committee member of 2^nd OLP Working Group （OLP Committee）, Japanese Association of Oral Medicine
Member of The Japanese Society of Oral Pathology
Yoshihiko SUGITA
Committee member of 2^nd OLP Working Group （OLP Committee）, Japanese Association of Oral Medicine
Member of The Japanese Society of Oral Pathology
Hiromasa HASEGAWA
Committee member of 2^nd OLP Working Group （OLP Committee）, Japanese Association of Oral Medicine
Member of The Japanese Society of Oral Pathology
Yuske KOMIYAMA
Department of Oral and Maxillofacial Surgery, Dokkyo Medical University School of Medicine
Ryo SHIRAISHI
Department of Oral and Maxillofacial Surgery, Dokkyo Medical University School of Medicine
Takahiro WAKUI
Department of Oral and Maxillofacial Surgery, Dokkyo Medical University School of Medicine

Keywords: oral lichen planus, treatment methods, clinical evaluation, chronic active phase, chronic nonactive phase

JOURNAL FREE ACCESS

2023 Volume 29 Issue 2 Pages 21-35

DOI https://doi.org/10.6014/jjsom.29.21

Details

Abstract

This article is a narrative review of current treatment methods and clinical evaluation of the outcome for oral lichen planus based on published articles （Japanese and international journals） by the 2^nd OLP Working Group of the OLP Committee of the Japanese Association of Oral Medicine. The result is summarized as a statement of the task force consensus. We hope that this review article will serve as an index for evaluating clinical and pathological efficacy in clinical trials to be conducted in Japan in the future. It is necessary to determine whether the status of oral lichen planus is acute phase or chronic phase on its pathobiology, or signs and symptoms. If chronic, it is necessary to determine whether it is a chronic active phase or a chronic nonactive phase. Therefore, it is necessary to select and develop the treatment methods while clarifying whether complete cure or maintenance of chronic nonactive phase is the goal of treatment, while keeping in mind the prevention of malignant transformation.

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