Pediatric complex regional pain syndrome successfully treated with pregabalin, clonazepam, and mirror therapy: a case report

Abstract

The present case study describes an 11-year-old boy, who presented with a 3-month history of right ankle pain and allodynia that developed after falling down while running at school. Following the investigation, a clinical diagnosis of complex regional pain syndrome (CRPS) was made. A pharmacotherapeutic agent, pregabalin, was administered at a low dose initially, which was subsequently increased. Additional treatment with mirror therapy and clonazepam was performed for complete recovery from allodynia. Over the period of three months, his condition gradually improved and no severe complications were observed. Moreover, during the follow-up period, symptoms recovered and there was no relapse. It is suggested that early diagnosis and management are the major factors for treating pediatric CRPS, and multidisciplinary treatment is recommended in such cases.