Journal of Japan Society of Pain Clinicians
Online ISSN : 1884-1791
Print ISSN : 1340-4903
ISSN-L : 1340-4903
Clinical Report
A case of remission of refractory eosinophilic gastroenteritis after treatment with Hangekobokuto: a case report
Sayuri TAKIYAMAKotaro HAMADATakafumi HORISHITA
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2025 Volume 32 Issue 6 Pages 135-138

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Abstract

Eosinophilic gastroenteritis is primarily an allergic disease. This report describes a case of eosinophilic gastroenteritis successfully treated with Hangekobokuto. Patient: 30-year-old male, height 173 cm, weight 65 kg. The patient presented with severe diarrhea. He was diagnosed with eosinophilic gastroenteritis and started taking 30 mg of prednisolone (PSL), which was gradually tapered off. In 16 months after onset, we prescribed Hangekobokuto at our pain clinic, and the diarrhea improved within a week, and the PSL dose was gradually reduced. The patient's symptoms did not flare up. Hangekobokuto was effective for eosinophilic gastroenteritis. Soyo, which is included in Hangekobokuto, suppresses the production of IgE antibodies. The constituent crude drugs Hange and Bukuryo have been shown to inhibit histamine release and leukotriene release. These were effective in the treatment of eosinophilic gastroenteritis.

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© 2025 Japan Society of Pain Clinicians
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