2021 Volume 57 Issue 2 Pages 251-256
Placental abruption is a major disease in obstetrics in terms of the need for rapid and accurate management. Therefore, clinicians need to be familiar with its clinical features. Although placental abruption can occur in extremely early gestational weeks, its clinical features are poorly understood because of its rarity. We performed a retrospective study to reveal the clinical characteristics of placental abruption, occurring between 22 and 28 gestational weeks. In the seven cases included in this study, the mean gestational age at onset was 26 weeks and 1 day. All patients had already known risk factors such as advanced maternal age, hypertensive disorders of pregnancy, and chorioamnionitis. In particular, there were three cases of histological chorioamnionitis. There was no maternal death. There was one intrauterine fetal death, one neonatal death, and two preterm infants who survived without sequelae. In our study, extremely early onset placental abruption tended to be associated with acute intrauterine inflammation. Thus, while treating diseases with an inflammatory background, such as premature rupture of membranes and preterm labor, special caution is required for the possible occurrence of placental abruption. The vital and neurological outcomes of children born after early-onset placental abruption were poor.
