Journal of Japan Society of Perinatal and Neonatal Medicine
Online ISSN : 2435-4996
Print ISSN : 1348-964X
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Risk factors for neonatal respiratory distress in single full-term infants in a general city hospital
Maki ToyamaTetsuhiro Sakihara
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2021 Volume 57 Issue 2 Pages 263-268

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Abstract

 Objective: To evaluate factors of neonatal respiratory distress(NRD)using perinatal information in general city hospitals, and develop a prediction tool for NRD.

 Methods: We developed a prediction model from factors related to NRD in the neonates born between January 2018 and December 2019(development dataset)and compared it with a prediction based on the presence of rapid delivery due to nonreassuring fetal status(NRFS). Receiver operating characteristic curve analyses were used to examine the predictive ability for NRD. The prediction ability for NRD was verified in the neonates born between January and December 2020(validation dataset).

 Results: Late term, cesarean section, rapid delivery due to NRFS, and umbilical cord arterial blood pH <7.12 were associated with NRD in development dataset which consists of 1,209 neonates including 73 of NRD. The prediction ability of the prediction model developed from them(area under the curve 0.69; 95% confidence interval 0.63–0.76)was equal to or higher than that of the prediction based on the presence of rapid delivery due to NRFS. The prediction ability of the prediction model was high even in validation dataset which consists of 649 neonates including 44 of NRD(area under the curve 0.66; 95% confidence interval 0.57-0.74).

 Conclusions: The predictive tool for NRD developed from factors below; late term, cesarean section, rapid delivery due to NRFS, and umbilical cord arterial blood pH, might be useful in neonatal care in general city hospitals.

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© 2021 Journal of Japan Society of Perinatal and Neonatal Medicine
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