Abstract
Biological activities of SB-PC against pseudomonas aeruginosa in bile were determined by the serial dilution method in 11 cases of biliary atresia 10 to 14 days after the operation and in 4 who were doing well without jaundice, 3 to 4 years after operation. The results were compared with those of adults (control group). The changes in concentration of SB-PC in serum in biliary atresia were similar to those in the control group. The concentration of SB-PC in bile was always higher than that in serum, and the highest level of the SB-PC in bile was 1, 705μg/ml in the control group. It was, however, very low and lower than 100μg/ml in biliary atresia in the early postoperative period inspite of good excretion of bile. SB-PC level in bile was about 3 times higher after 3 or 4 years after the operation comparing with that in the early postoperative period, but still lower than that of the control group.
