Two cases of unfavorable histology Wilms' Tumor and a Review of the Japanese Literature

Abstract

Two cases of a four-month-old boy with malignant rhabdoid tumor of the kidney (MRTK) and a one and a half-year-old girl with clear cell sarcoma of the kidney (CCSK) are presented. They were treated by surgery, radiation therapy and chemotherapy according to the regimen-DD of the Third National Wilms' Tumor Study. They are alive without tumors after 38 months and 35 months after therapy, respectively. Twenty-two CCSK patients and 14 MRTK patients have been reported in Japanese literature. Seven CCSK and 3 MRTK patients stayed alive without tumors for more than 2 years after diagnosis.