Abstract
To investigate injury of arterial wall with canulation technique, an experimental study was performed with a rabbit model of canulation to right common carotid artery (RCCA). After 3-7 days, segments of the RCCA were excised and examined histologically. Arteriotomy sites in the segments of the RCCA were compared with more proximal parts. Histrogical findings revealed that arterial walls were more severely injured in the arteriotomy sites than in the proximal parts. Therfore, end-to-end anastomosis after excision of arteriotomy sites was proposed for reconstruction of the RCCA. From this experimental study, we learned to make reconstruction of the RCCA in 4 neonates treated with extracorporeal membrane oxygenation (ECMO). Repaired RCCAs with end-to-end anastomosis were patent without significant stenosis, and no signs of unilateral brain injury appeared. These findings suggested that reconstruction of the carotid artery could be performed safely.
