Abstract
We experienced three cases of the Ewing Sarcoma Family of Tumors, including a pelvic lesion in a 15-year old male, a retroperitoneal in a 7-year old female and a subcutaneous in a 6-year old female. In addition to the surgical treatments, we adopted various chemotherapeutic regimens considering the situations in each patient, including primary site, tumor size, age and reaction to the initial chemotherapy. Two patients have been healthy in a disease-free state and the other died of a cause unrelated to the tumor. The Ewing Sarcoma Family of Tumors has a high malignant potential, and tumor size or volume, primary site (pelvic and paraspinal), age (more than 10 years old), resistance to the initial chemotherapy, distant metastasis and differentiation to neurogenic components seem to be indicators of poor prognosis. In Japan, there is no protocol which has proved to be effective so that a nationwide group study is called for.
