抄録
[14C] arachidonic acid and [3H] myoinositol double labelled platelet membrane vesicles were prepared from human platelet. Upon the stimulation of [14C] arachidonic acid and [3H] myoinositol labelled platelet membrane vesicles by thrombin, the formation of not free arachidonic acid but diglycerides was observed. Simultaneously, a decrease in radioactivity was observed not in the pool of phosphatydylcholine but in that of phosphatidylinositol. From these observation, it may be considered that platelet membrane vesicle is devoid of diglyceride lipase and that not phospholipase A2 but phospholipase C is involved in the early step of platelet aggregating reaction.
