抄録
As biological characterization of ATIII in patients with liver cirrhosis, the discrepancy between it's progressive activity and heparin cofactor activity obtained from biological measurements determined by clotting method with it's neutralized ability to thrombin or FXa. Both of heparin cofactor activities to thrombin and FXa reduced significantly in comparison with that's progressive activities in patients with liver cirrhosis. By crossed immunoelectrophoresis with heparin agar, the fast moving peak formed with ATIII and heparin was markdly smaller than that of normal plasmas. It might be thought that ATIII affinity to heparin was more reduced in plasma from liver cirrhosis than it's affinity in normal plasma.
