Abstract
The effects of hepatic lobectomy on some blood clotting factors, blood biochemical examinations and fibrinolytic activity were studied on seven patients, and also on dogs under-going seventy per cent hepatic lobectomy.
Experimental data showed that prothrombin time, the amounts of fibrinogen and transaminase unit returned to normal range within two weeks after operation.
Alkaline phosphatase unit rose later than transaminase unit but former took longer time to return preoprative value than later.
Clinical data showed that when the resected liver remaind below fifty per cent, fibrinolytic activity and clotting disorders returned to normal range within three weeks after hepatectomy.
In all but two patients, liver echinococcosis with liver fibrosis and total right hepatic lobectomy, continued the prolongation of prothrombin time and fibrinolytic activity of the euglobulin fraction till three or more weeks.
we considerd that prolongation of prothrombin time and shortening of euglobulin clot lysis time caused not only because the synthetic disturbance of factors and consumption of clotting factors but also because the results of spontaneous liver circulating insufficiency causing of hyper portal pressure.
