A CASE WITH ANTI-E ANTIBODIES PRODUCED BY PLATELET TRANSFUSION

Abstract

We experienced a case of anti-E. This patient has both anti-f and anti-c, despite receiving a red blood cell transfusion from apparently R₁R₁ (CCDee) donors.

This history suggests that the cause might have been alloimmunization by platelet transfusion. We examined the existence of Rh-Hr type in 10 packs of transfused PC. As a result, 4 of 10 packs showed the R₁R₂ (CcDEe) type. Further, 2 packs had been administered before the anti-E appearance.

This suggests that the E-antigen in the PC bags might have produced anti-E antibodies. There may be the possibility of antibody production by platelet transfusion with the inclusion of a few red blood cells.