2017 Volume 63 Issue 1 Pages 3-8
The existence of maternal anti-A and/or anti-B antibodies has to be clarified in selecting ABO-blood type for red blood cell (RBC) transfusion in infants aged up to 4 months. In Okayama University Hospital, we have not had a standardized policy for ABO-blood type selection based on the results of assays for maternal anti-A and anti-B antibodies in patients. In this study, we retrospectively reviewed the data about selecting ABO-blood type for RBC transfusion in infants aged up to 4 months with anti-A and/or anti-B antibodies between April 2009 and March 2013.
There were 44 cases (14.2%) where maternal anti-A and/or anti-B antibodies were detected by indirect antiglobulin tests among 309 patients of blood type A, B, or AB aged up to 4 months. Blood type O was selected for 24 of the 44 cases, while the same blood type as that reported for the respective patients was selected 20 cases. Hemolysis was not reported in any cases, however, there were 17 cases of positive agglutination in back typing blood tests using the same patients' ABO-blood type by column agglutination technology. This back typing blood test by column agglutination technology that detected maternal anti-A and anti-B IgG antibodies might be useful for determining ABO-blood type for transfusion.