Journal of the Japan Society of Blood Transfusion
Online ISSN : 1883-8383
Print ISSN : 0546-1448
ISSN-L : 0546-1448
DEXTRAN-GEL FRACTIONATION OF ANTI-rh″ (E), ANTI-hr′ (c) AND ANTI-A IN A PATIENT WITH TRANSFUSION REACTIONS
Hayato HASEKURAKenji KONDOYoshio HAYAMAOsamu TAKIGAWAHisayuki FUKUTOMI
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1966 Volume 12 Issue 6 Pages 167-172

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Abstract
A case was reported of group B, Rh1Rh1 (CCDee) woman who produced anti-rh″ (anti-E) and anti-hr′ (anti-c) by incompatible transfusions.
Characterization of the antibodies, performed through dextran-gel (Sephadex G-200) filtration and 2-mercaptoethanol treatment, revealed that anti-rh″ (anti-E) consisted of potent saline active 19S fraction and potent anti-globulin active 7S fraction, anti-hr′ (antic) consisted of less potent anti-globulin active 19S fraction as well as less potent anti-globulin active 7S fraction, and anti-A consisted of moderate saline active 19S fraction and very weak anti-globulin active 7S fraction.
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© The Japan Society of Transfusion Medicine and Cell Therapy
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