Abstract
Clinical evaluation of screening test by SGO-T determination for blood donors were studied with using simple rapid procedure (Whetzel method) in order to seek for possibility of preventing viral hepatitis after blood transfusion.
More than 74, 000 blood donors were tested by this screening procedure. Comparative studies on the incidence of viral hepatitis after transfusion were made by observation in 5, 375 cases of recipients who were given with the screened blood and in the control group of 6, 830 cases of recipients given with the blood which was not screened. The results obtained were summarized as follows:
1) A linear relationship was found to exist between the regular Reitman-Frankel procedure and simple rapid screening test in the determination of SGO-T level with the base of judgement fixed in 40 units. It was fou nd that SGO-T screening test has a sufficient accuracy and specificity for blood donor screening.
2) Approximately 7% of paid donors and 2% of voluntary donors were screened out by simple rapid procedure of SGO-T determination.
3) The incidence of viral hepatitis after blood transfusion was observed at the rate of 6.2% in the cases of recipient who were given with the blood screened by Whetzel simple rapid procedure. This rate of the incidence was only a half in comparison with cases of recipients with the blood which was not screened as control.
These results suggest that SGO-T screening test for blood donor by Whetzel procedure is useful to reduce the incidence of hepatitis caused by blood transfusion.
